Progesterone (Standard)

By Targets:	Progesterone Receptor (7) Androgen Receptor (1) Autophagy (2) Endogenous Metabolite (2) Glucocorticoid Receptor (2) HIV (1) NO Synthase (1) Reactive Oxygen Species (1)
By Research Areas:	Cancer (6) Cardiovascular Disease (1) Endocrinology (5) Metabolic Disease (1) Neurological Disease (1)

Targets Recommended: Progesterone Receptor

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-N0437R

Progesterone (Standard) 15+ Cited Publications Pregn-4-ene-3,20-dione (Standard)	Progesterone Receptor Endogenous Metabolite	Cardiovascular Disease Cancer
Progesterone (Standard) is the analytical standard of Progesterone. This product is intended for research and analytical applications. Progesterone is a steroid hormone that regulates the menstrual cycle and is crucial for pregnancy.

HY-B0469R

Medroxyprogesterone acetate (Standard) 10+ Cited Publications MedroxyProgesterone 17-acetate(Standard); Farlutin (Standard)	Progesterone Receptor Androgen Receptor Glucocorticoid Receptor Endogenous Metabolite	Endocrinology Cancer
Medroxyprogesterone acetate (Standard) is the analytical standard of Medroxyprogesterone acetate. This product is intended for research and analytical applications. Medroxyprogesterone acetate is a widely used synthetic steroid by its interaction with *progesterone, androgen* and glucocorticoid receptors .

HY-13683R

Mifepristone (Standard) Maximum Cited Publications 32 Publications Verification RU486 (Standard); RU 38486 (Standard)	Progesterone Receptor Glucocorticoid Receptor NO Synthase Autophagy	Endocrinology Cancer
Mifepristone (Standard) is the analytical standard of Mifepristone. This product is intended for research and analytical applications. Mifepristone (RU486) is a progesterone receptor (PR) and glucocorticoid receptor (GR) antagonist with IC₅₀s of 0.2 nM and 2.6 nM in in vitro assay .

HY-B0257AR

Dydrogesterone (Standard)	Progesterone Receptor	Endocrinology
Dydrogesterone (Standard) is the analytical standard of Dydrogesterone. This product is intended for research and analytical applications. Dydrogesterone is a potent, orally active progestogen indicated in a wide variety of gynaecological conditions related to progesterone deficiency.

HY-W013172R

Norgestimate (Standard)	Progesterone Receptor	Endocrinology
Norgestimate (Standard) is the analytical standard of Norgestimate. This product is intended for research and analytical applications. Norgestimate, a synthetic progesterone analog, is an orally active progestin with highly selective progestational activity and minimal androgenicity. Norgestimate is used for an oral contraceptive .

HY-N7137R

Norgestrel (Standard)	Reactive Oxygen Species	Neurological Disease Cancer
Norgestrel (Standard) is the analytical standard of Norgestrel. This product is intended for research and analytical applications. Norgestrel is a synthetic analog of progesterone, a compound commonly found in oral contraceptive pill, and a powerful neuroprotective antioxidant, preventing light-induced ROS in photoreceptor cells, and cell death .

HY-13676R

Megestrol acetate (Standard)	Progesterone Receptor Autophagy HIV	Endocrinology Cancer
Megestrol acetate (Standard) is the analytical standard of Megestrol acetate. This product is intended for research and analytical applications. Megestrol acetate is a synthetic and orally active progesteronal agent. Megestrol acetate is effective as an appetite stimulant for wasting syndromes such as cachexia. Megestrol acetate decreases nuclear and cytosol androgen receptors human BPH tissue. Megestrol acetate has the potential for HIV study and downregulates autophagic catabolic pathway .

HY-111614R

Melengestrol acetate (Standard)	Progesterone Receptor	Metabolic Disease Cancer
Melengestrol acetate (Standard) is the analytical standard of Melengestrol acetate. This product is intended for research and analytical applications. Melengestrol acetate is a progesterone derivative, acts as an orally active corticosteroid hormone to promote endometrial proliferation, pregnancy maintenance, and delay of menstrual activity . Melengestrol Acetate is used as a contraceptive agent for growth promoting effects and suppression of estrus in animals. Melengestrol acetate inhibits both the androgen-dependent and -independent prostatic tumors in vivo and can be used for cancer research .

Cat. No.	Product Name

HY-L074

Anti-Breast Cancer Compound Library	1968 compounds
Breast cancer is the most frequent cancer among women, impacting 2.1 million women each year, and also causes the greatest number of cancer-related deaths among women. Surgery is usually the first type of treatment for breast cancer, which is usually followed by chemotherapy or radiotherapy or, in some cases, hormone or targeted therapies, especially for metastatic breast cancer (MBC). Breast cancer is a heterogeneous disease, which is categorized into 3 major subtypes based on the presence or absence of molecular markers for estrogen or progesterone receptors and human epidermal growth factor 2 (ERBB2; formerly HER2): hormone receptor positive/ERBB2 negative (70% of patients), ERBB2 positive (15%-20%), and triple-negative (tumors lacking all 3 standard molecular markers; 15%). Different intrinsic subtypes exhibit different tumor behavior with different prognoses, and may require specific targeted therapies to maximize treatment effectiveness. Otherwise, some signaling pathways also play important roles in the development of breast cancer, such as NF-κB Signaling Pathway, TGF-beta Signaling Pathway, PI3K/AKT/mTOR signaling pathway and Notch Signaling Pathway. These signaling pathways offer ideal targets for development of new targeted therapies for breast cancer. MCE supplies a unique collection of 1968 compounds with identified and potential anti-breast cancer activity. MCE Anti-Breast Cancer Compound Library is a useful tool for anti-breast cancer drugs screening.

Anti-Breast Cancer Compound Library

1968 compounds

Breast cancer is the most frequent cancer among women, impacting 2.1 million women each year, and also causes the greatest number of cancer-related deaths among women. Surgery is usually the first type of treatment for breast cancer, which is usually followed by chemotherapy or radiotherapy or, in some cases, hormone or targeted therapies, especially for metastatic breast cancer (MBC).

Breast cancer is a heterogeneous disease, which is categorized into 3 major subtypes based on the presence or absence of molecular markers for estrogen or progesterone receptors and human epidermal growth factor 2 (ERBB2; formerly HER2): hormone receptor positive/ERBB2 negative (70% of patients), ERBB2 positive (15%-20%), and triple-negative (tumors lacking all 3 standard molecular markers; 15%). Different intrinsic subtypes exhibit different tumor behavior with different prognoses, and may require specific targeted therapies to maximize treatment effectiveness. Otherwise, some signaling pathways also play important roles in the development of breast cancer, such as NF-κB Signaling Pathway, TGF-beta Signaling Pathway, PI3K/AKT/mTOR signaling pathway and Notch Signaling Pathway. These signaling pathways offer ideal targets for development of new targeted therapies for breast cancer.

MCE supplies a unique collection of 1968 compounds with identified and potential anti-breast cancer activity. MCE Anti-Breast Cancer Compound Library is a useful tool for anti-breast cancer drugs screening.

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N0437R

Progesterone (Standard) 15+ Cited Publications Pregn-4-ene-3,20-dione (Standard)	Structural Classification Classification of Application Fields Other disease Source classification Disease markers Endogenous metabolite Disease Research Fields Steroids Cancer	Progesterone Receptor Endogenous Metabolite
Progesterone (Standard) is the analytical standard of Progesterone. This product is intended for research and analytical applications. Progesterone is a steroid hormone that regulates the menstrual cycle and is crucial for pregnancy.

HY-B0469R

Medroxyprogesterone acetate (Standard) 10+ Cited Publications MedroxyProgesterone 17-acetate(Standard); Farlutin (Standard)	Structural Classification Classification of Application Fields Source classification Endogenous metabolite Disease Research Fields Steroids Cancer	Progesterone Receptor Androgen Receptor Glucocorticoid Receptor Endogenous Metabolite
Medroxyprogesterone acetate (Standard) is the analytical standard of Medroxyprogesterone acetate. This product is intended for research and analytical applications. Medroxyprogesterone acetate is a widely used synthetic steroid by its interaction with *progesterone, androgen* and glucocorticoid receptors .

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Progesterone (Standard)

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